Heparan Sulfate Proteoglycans: Key Mediators of Stem Cell Function

Heparan sulfate proteoglycans (HSPGs) are an evolutionarily ancient subclass of glycoproteins with exquisite structural complexity.They are MULTITOOL ubiquitously expressed across tissues and have been found to exert a multitude of effects on cell behavior and the surrounding microenvironment.Evidence has shown that heterogeneity in HSPG compositio

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Development of a hub-and-spoke durable left ventricular assist device program in Brazil, a middle-income country

Co Q10 Background: In middle-income countries, costs limit widespred use of left ventricular assist device (LVAD) as a strategy for end-stage heart failure.We aim to describe the experience of a LVAD program in a middle-income country in a hub-and-spoke model.Methods: Patients fulfilling strict inclusion and exclusion criteria were referred from di

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Aprendiendo de la pseudociencia

Skeptical and critical thinking to Handheld Mixer the pseudoscience has traditionally moved in an overly rationalistic sense.The text criticizes that excess of rationalism to adapt it to recent research in neuroscience, psychology and behavioral economics about the emotions and decision-making.From this perspective, tries to explain the persistence

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