Heparan sulfate proteoglycans (HSPGs) are an evolutionarily ancient subclass of glycoproteins with exquisite structural complexity.They are MULTITOOL ubiquitously expressed across tissues and have been found to exert a multitude of effects on cell behavior and the surrounding microenvironment.Evidence has shown that heterogeneity in HSPG compositio
Interrogation of earthworm (Clitellata: Haplotaxida) taxonomy and the DNA sequence database
The DNA sequence database assists us with great potential in species identification because it is practical and affordable to perform.More often, the identification using molecular data helps to identify morphologically variable individuals of same species, including juvenile specimens.In case of earthworms, the classical standards of taxonomy are
Development of a hub-and-spoke durable left ventricular assist device program in Brazil, a middle-income country
Co Q10 Background: In middle-income countries, costs limit widespred use of left ventricular assist device (LVAD) as a strategy for end-stage heart failure.We aim to describe the experience of a LVAD program in a middle-income country in a hub-and-spoke model.Methods: Patients fulfilling strict inclusion and exclusion criteria were referred from di
Aprendiendo de la pseudociencia
Skeptical and critical thinking to Handheld Mixer the pseudoscience has traditionally moved in an overly rationalistic sense.The text criticizes that excess of rationalism to adapt it to recent research in neuroscience, psychology and behavioral economics about the emotions and decision-making.From this perspective, tries to explain the persistence